Clarivate analytics endnote5/25/2023 ![]() When expressed, efflux proteins self-assemble to form multiprotein complexes and actively expel highly toxic compounds out of the host organism. Several MarR-like proteins, including MexR, repress the expression of efflux pump proteins by binding to DNA on regulatory sites overlapping with promoter regions. ![]() ![]() Please use a persistent id in citations: doi: 10.1016/j.bpj.20 doi: 10.3204/PUBDB-2023-01359Ībstract: In this work, we used small-angle x-ray and neutron scattering to reveal the shape of the protein-DNA complex of the Pseudomonas aeruginosa transcriptional regulator MexR, a member of the multiple antibiotics resistance regulator (MarR) family, when bound to one of its native DNA binding sites. ![]()
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